1,737 research outputs found
How Close Are We to Solving the Puzzle? Review of the Alopecia Areata Research Workshop David Norris
Writing about war: making sense of the absurd in Mileta Prodanović's novel Pleši, čudovište, na moju nežnu muziku (Dance, you monster, to my soft music)
In the narrative of a mass conflict, the human experience of its effects may be subsumed into the rationalizing contours of history, or they may fall completely outside our comprehension. This article examines the intertextual strategies employed in Prodanović's novel about the war in former Yugoslavia. The text conveys the reality of the conflict by relating it through events and characters located in prior media constructions. The historical, documentary, mythic, and fictional sources focus on the signifying systems which drag the war into the horizon of expectations of those who were not there, closing the gap between reality and representation, life and art
Impact glasses from the less than 20-micrometer fraction of Apollo 17 soils 72501 and 78221
The chemical compositions of microscopic glasses produced during meteoroid impacts on the lunar surface provide information regarding the various fractionation processes that accompany these events. To learn more about these fractionation processes, we studied the compositions of submicrometer glass spheres from two Apollo 17 sampling sites using electron microscopy. The majority of the analyzed glasses show evidence for varying degrees of impact-induced chemical fractionation. Among these are HASP glasses (high-Al, Si-poor), which are believed to represent the refractory residuum left after the loss of volatile elements (e.g., Si, Fe, Na) from the precursor material. In addition to HASP-type glasses, we also observed a group of volatile-rich, Al-poor (VRAP) glasses that represent condensates of vaporized volatile constituents, and are complementary to the HASP compositions. High-Ti glasses were also found during the course of this study, and are documented here for the first time
Influence of Inflammatory Mediators and Cytokines on Human Melanocyte Function
The fully differentiated human melanocyte functions as a necessary and integral part of the epidermis, synthesizing melanin in intracellular organelles and transferring these pigment-containing organelles to surrounding keratino-cytes. The epidermal environment contains multiple inflammatory mediators, cytokines, and growth factors that may alter constitutive melanocyte function. Constitutive melanocyte function can also be markedly altered by release of such mediators in inflammatory dermatoses. Many of the same factors can also be released by ultraviolet radiation and psoralen + ultraviolet A treatment. These inflammatory mediators and cytokines affect not only melanocyte pigment production, but also proliferation, differentiation, immunologic susceptibility and cytotoxicity, inflammatory mediator, cytokine and matrix protein production, and cell movement. The effect of inflammatory mediators and cytokines on melanocytes and the regulation of these effects are an active area of investigation. J Invest Dermatol 100:191S–195S, 199
ECO and RESOLVE: Galaxy Disk Growth in Environmental Context
We study the relationships between galaxy environments and galaxy properties
related to disk (re)growth, considering two highly complete samples that are
approximately baryonic mass limited into the high-mass dwarf galaxy regime, the
Environmental COntext (ECO) catalog (data release herein) and the B-semester
region of the REsolved Spectroscopy Of a Local VolumE (RESOLVE) survey. We
quantify galaxy environments using both group identification and smoothed
galaxy density field methods. We use by-eye and quantitative morphological
classifications plus atomic gas content measurements and estimates. We find
that blue early-type (E/S0) galaxies, gas-dominated galaxies, and UV-bright
disk host galaxies all become distinctly more common below group halo mass
~10^11.5 Msun, implying that this low group halo mass regime may be a preferred
regime for significant disk growth activity. We also find that blue early-type
and blue late-type galaxies inhabit environments of similar group halo mass at
fixed baryonic mass, consistent with a scenario in which blue early types can
regrow late-type disks. In fact, we find that the only significant difference
in the typical group halo mass inhabited by different galaxy classes is for
satellite galaxies with different colors, where at fixed baryonic mass red
early and late types have higher typical group halo masses than blue early and
late types. More generally, we argue that the traditional
morphology-environment relation (i.e., that denser environments tend to have
more early types) can be largely attributed to the morphology-galaxy mass
relation for centrals and the color-environment relation for satellites.Comment: 26 pages and 28 figures; v2 contains minor figure and text updates to
match final published version in ApJ; ECO data table release now available at
http://resolve.astro.unc.edu/pages/data.ph
Measurement of activation-related changes in cerebral blood volume: VASO with single-shot HASTE acquisition
Object The recently developed vascular space occupancy (VASO) fMRI technique is gaining popularity as it facilitates the measurement of cerebral blood volume (CBV) changes concomitant with brain activation, without the use of contrast agents. Thus far, VASO fMRI has only been used in conjunction with a GE-EPI (gradient-echo echo planar imaging) sequence, which is proceeded by an inversion recovery (IR) experiment to selectively null the blood signal. The use of GE-EPI has potential disadvantages: (a) the non-zero TE may lead to BOLD contamination and (b) images suffer from the EPI-typical inhomogeneity artefacts
Gestational diabetes mellitus in Africa: a systematic review.
BACKGROUND: Gestational diabetes mellitus (GDM) is any degree of impaired glucose tolerance first recognised during pregnancy. Most women with GDM revert to normal glucose metabolism after delivery of their babies; however, they are at risk of developing type 2 diabetes later in life as are their offspring. Determining a country's GDM prevalence can assist with policy guidelines regarding GDM screening and management, and can highlight areas requiring research. This systematic review assesses GDM prevalence in Africa. METHODS AND FINDINGS: Three electronic databases were searched without language restrictions; PubMed, Scopus and the Cochrane Library. Thirty-one search terms were searched. Eligible articles defined GDM, stated what GDM screening approaches were employed and reported GDM prevalence. The reporting quality and risk of bias within each study was assessed. The PRISMA guidelines for systematic reviews were followed. The literature search identified 466 unique records. Sixty full text articles were reviewed of which 14 were included in the systematic review. One abstract, for which the full text article could not be obtained, was also included. Information regarding GDM classification, screening methods and prevalence was obtained for six African countries; Ethiopia (n = 1), Morocco (n = 1), Mozambique (n = 1), Nigeria (n = 6), South Africa (n= 4) and Tanzania (n = 1). Prevalence figures ranged from 0% (Tanzania) to 13.9% (Nigeria) with some studies focussing on women with GDM risk factors. Most studies utilised the two hour 75 g oral glucose tolerance test and applied the World Health Organization's diagnostic criteria. CONCLUSIONS: Six countries, equating to 11% of the African continent, were represented in this systematic review. This indicates how little is known about GDM in Africa and highlights the need for further research. Considering the increasing public health burden of obesity and type 2 diabetes, it is essential that the extent of GDM is understood in Africa to allow for effective intervention programmes.This is the final published version of the article. It was originally published here: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0097871
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